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Wednesday, April 25, 2007

Antisocial Behavioral Syndromes and DSM-IV Alcohol Use Disorders: Results From the National Epidemiologic Survey on Alcohol and Related Conditions
Alcoholism: Clinical and Experimental Research 31 (5), 814–828.

Antisocial personality disorder (ASPD), syndromal adult antisocial behavior (AABS) without conduct disorder (CD) before age 15, and CD without progression to ASPD ("CD only") are highly prevalent among adults with alcohol use disorders (AUDs).

This study examines prevalences and correlates of antisocial syndromes among adults with lifetime Diagnostic and Statistical Manual—Version IV (DSM-IV) AUDs, and describes associations of these syndromes with clinical characteristics of AUDs, in the general U.S. population.

Antisocial syndromes were significantly associated with phenomenology of AUDs, particularly ASPD with the most severe clinical presentations. Associations with AABS were similar to but more modest than those with ASPD; those with "CD only" were weaker and less consistent.

Patterns of associations between antisocial syndromes and clinical characteristics of AUDs were generally similar between men and women.

Antisocial syndromes, particularly ASPD, appear to identify a more pernicious clinical profile of AUDs among adults in the general U.S. population.