Aims

To support the free and open dissemination of research findings and information on alcoholism and alcohol-related problems. To encourage open access to peer-reviewed articles free for all to view.

For full versions of posted research articles readers are encouraged to email requests for "electronic reprints" (text file, PDF files, FAX copies) to the corresponding or lead author, who is highlighted in the posting.

___________________________________________

Saturday, January 5, 2008

Dose-response relation between volume of drinking and alcohol-related diseases in male general hospital inpatients
Alcohol and Alcoholism Advance Access published online on November 25, 2007



Previous studies investigating dose-response relations between volume of drinking and diseases have focused on single diseases only. Until now, the relation between the drinking volume and the risk of having any alcohol-attributable disease is largely unknown.

The aim of the present study is to investigate to what extent is the risk of diseases with different alcohol-attributable fractions (AAFs) predicted by daily alcohol consumption (> 120 g, 61–120 g vs 31–60 g).

In our sample, 26.6% of the inpatients showed a disease with AAF = 1, while 20.2% had a disease with AAF <> consuming > 120 g, and inpatients consuming 61–120 g revealed significantly higher odds for diseases with AAF = 1 compared to inpatients consuming 31–60 g (OR = 6.30, CI = 3.55–11.26; OR = 2.91, CI = 1.64–5.13).

Regarding diseases with AAF <> 120 g revealed significantly higher odds compared to the inpatients consuming 31–60 g (OR = 1.97, CI = 1.15–3.37).

A dose-response relation between the level of the drinking volume and the risk of diseases with AAF = 1 was found in this sample of inpatients from the general hospitals.


Read Full Abstract

Request Reprint E-Mail: katharina.lau@uni-greifswald.de

_______________________________________________________________



at