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For full versions of posted research articles readers are encouraged to email requests for "electronic reprints" (text file, PDF files, FAX copies) to the corresponding or lead author, who is highlighted in the posting.
___________________________________________
Sunday, August 25, 2013
Biochemical Predictors of Delirium Tremens in Patients in Alcohol Withdrawal
To study whether routine blood parameters in patients with alcohol syndrome predict the risk of developing delirium tremens.
Biochemical parameters were collected and analysed in 212 patients attending a psychiatry department for inpatient alcohol detoxification treatment.
Differences between those who did, and did not, develop delirium were observed in baseline platelet count , total leucocyte count , red cell distribution width , serum bilirubin , aspirate amino transferase (AST) and alanine aminotransferase (ALT) . Baseline platelet count predicted the development of delirium.
Baseline platelet count was an independent risk factor for delirium tremens. Serum AST and total WBC count , although not significant as independent risk factors, showed high specificity and predictive value in conjunction with low platelet count and/or previous history of delirium tremens. A normal baseline platelet count nearly rules out development of delirium tremens in patients with alcohol withdrawal in this population.
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