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Sunday, March 25, 2007

Family History of Alcoholism Influences Naltrexone-Induced Reduction in Alcohol Drinking

The purpose of this study was to examine the interactive effects of family history of alcoholism (FH+, FH−) and naltrexone dose (0, 50, 100 mg/day) on alcohol drinking.

These results suggest that family history of alcoholism might be a significant clinical predictor of response to naltrexone and that FH+ men are more likely to benefit from naltrexone therapy for alcohol drinking.