In recent years, baclofen demonstrated its ability to reduce symptoms of severe alcohol withdrawal syndrome (AWS) in alcoholic patients, without producing any significant side effects.
This review attempted to evaluate if baclofen is generally effective and safe as a therapy for AWS.
Among the pertinent literature, there was only one study meeting our inclusion criteria. In general, baclofen is efficacious, safe and well tolerated for the treatment of AWS.
The evidence of recommending baclofen for AWS is insufficient.
More well designed randomised controlled clinical trials (RCTs) are demanded to further prove its efficacy and safety.
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This review attempted to evaluate if baclofen is generally effective and safe as a therapy for AWS.
Among the pertinent literature, there was only one study meeting our inclusion criteria. In general, baclofen is efficacious, safe and well tolerated for the treatment of AWS.
The evidence of recommending baclofen for AWS is insufficient.
More well designed randomised controlled clinical trials (RCTs) are demanded to further prove its efficacy and safety.
Read Full Abstract
