Alcohol drinking cessation and its effect on esophageal and head and neck cancers: A pooled analysis

International Journal of Cancer Volume 121, Issue 5 , Pages 1132 - 1137

The objective of this study was to conduct a pooled analysis to evaluate the strength of the evidence available in the epidemiological literature on the association between alcohol drinking cessation and reduction in esophageal and head and neck cancer risks. The risk of esophageal cancer significantly increased within the first 2 yr following cessation then decreased rapidly and significantly after longer periods of abstention . An elevated risk, although not strong as for esophageal cancer, was observed for head and neck cancer up to 10 yr of quitting drinking. Such risk only reduced after 10 yr of cessation . After more than 20 yr of alcohol cessation, the risks for both cancers were no longer significantly different from the risk of never drinkers. Our findings demonstrate an important role of alcohol cessation on esophageal and head and neck carcinogenesis. Read Full Abstract Reprint Request E-Mail: jtrehm@aol.com ___________________________________________________________________