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Monday, September 7, 2009

The Activity of Lysosomal Exoglycosidases in Serum of Alcohol-Dependent Men Supplemented with Borage Oil Enriched with Vitamin E
Journal of Medicinal Food. August 2009, 12(4): 914-918.

The aim of this study was to determine the activity of the lysosomal exoglycosidases: α-mannosidase (MAN), α-fucosidase (FUC), and β-glucuronidase (GLUCUR) in serum of alcohol-dependent men supplemented and not supplemented with borage oil enriched with vitamin E.

Specific activity of FUC in serum of alcohol-dependent men both not supplemented and supplemented with borage oil enriched with vitamin E showed a tendency to increase, in comparison with social drinkers. Specific activity of FUC had a tendency to decrease in serum of alcohol-dependent men supplemented with borage oil enriched with vitamin E, in comparison with alcohol-dependent men not supplemented.

Thus, supplementation of alcohol-dependent men after a long-lasting drinking period with borage oil and vitamin E did not change the rate of catabolism of the oligosaccharide chains of glycoconjugates, as evaluated by serum activity of exoglycosidases.


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