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Wednesday, May 21, 2008

Review of Australian health economic evaluation- 245 interventions: what can we say about cost-effectiveness?
Cost Effectiveness and Resource Allocation 2008, 6:9

There is an increasing body of published cost-utility analyses of health interventions which we sought to draw together to inform research and policy.

The median cost-effectiveness ratio was $18,100 (~US$13,000) per QALY/DALY/LY (quality adjusted life year gained or, disability adjusted life year averted or life year gained). Some modalities tended to perform worse, such as vaccinations and diagnostics (median cost/QALY $58,000 and $68,000 respectively), than others such as allied health, lifestyle, in-patient interventions (median cost/QALY/DALY/LY all at ~A$9,000 ~US$6,500).

Interventions addressing some diseases such as diabetes and impaired glucose tolerance or alcohol and drug dependence tended to perform well (median cost /QALY/DALY/ LY 25 years (median cost /QALY/DALY/ LY

For any given condition, modality or setting there are likely to be examples of interventions that are cost effective and cost ineffective. It will be important for decision makers to make decisions based on the individual merits of an intervention rather than rely on broad generalisations. Further evaluation is warranted to address gaps in the literature and to ensure that evaluations are performed in areas with greatest potential benefit.


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