The purpose of this study was to examine the interactive effects of family history of alcoholism (FH+, FH−) and naltrexone dose (0, 50, 100 mg/day) on alcohol drinking.
These results suggest that family history of alcoholism might be a significant clinical predictor of response to naltrexone and that FH+ men are more likely to benefit from naltrexone therapy for alcohol drinking.
REQUEST REPRINT E-MAIL: suchitra.krishnan-sarin@yale.edu
____________________________________________________________