Aims

To support the free and open dissemination of research findings and information on alcoholism and alcohol-related problems. To encourage open access to peer-reviewed articles free for all to view.

For full versions of posted research articles readers are encouraged to email requests for "electronic reprints" (text file, PDF files, FAX copies) to the corresponding or lead author, who is highlighted in the posting.

___________________________________________

Sunday, March 25, 2007

The effects of alcohol on laboratory-measured impulsivity after l -Tryptophan depletion or loading

Indirect evidence supports a link between serotonergic activity and individual differences in the behavioral response to alcohol, but few studies have experimentally demonstrated that an individual’s biological state can influence the sensitivity to alcohol-induced behaviors.

These findings demonstrate that reduced serotonin synthesis can produce increased impulsivity even among non-impulsive normal controls, and that the behavioral effects of alcohol are, in part, dependent on this biological state.

READ FULL ABSTRACT

REQUEST REPRINT E-MAIL: ddougher@wfubmc.edu