Aims

To support the free and open dissemination of research findings and information on alcoholism and alcohol-related problems. To encourage open access to peer-reviewed articles free for all to view.

For full versions of posted research articles readers are encouraged to email requests for "electronic reprints" (text file, PDF files, FAX copies) to the corresponding or lead author, who is highlighted in the posting.

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Sunday, April 13, 2008

News Release - How What and How Much We Eat (And Drink) Affects Our Risk of Cancer
April 13, 2008

SAN DIEGO - A healthy diet and lifestyle protect against a wide range of diseases, and new research presented at the American Association for Cancer Research 2008 Annual Meeting, April 12-16, shows that cancer is no exception. Researchers demonstrate how excessive alcohol drinking could lead to an increased risk of breast cancer, how consuming too many calories may increase one's risk for melanoma, and why with folic acid, timing is everything for colon cancer prevention.

Alcohol consumption and risk of breast cancer in postmenopausal women: the NIH-AARP Diet and Health Study: Abstract 4168

One of the largest studies of its kind has found that alcohol is a substantial risk factor for development of the most common type of breast cancer - the 70 percent of tumors that are classified as positive for both the estrogen and progesterone receptors (ER+/PR+). Researchers report that even moderate alcohol consumption, defined as one or two drinks per day, increased risk of developing this kind of cancer, and the more a woman drank, the higher her risk. Compared to women who did not drink at all, women who had three or more glasses of alcohol daily had as much as a 51 percent increased risk of ER+/PR+ breast cancer.
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Association Between ADH1B and ADH1C Haplotype Tag SNPs and Breast Cancer Risk, and the Interaction with Alcohol Drinking: Abstract 5814

Specific variations within two genes involved with alcohol metabolism are associated with an increased risk for breast cancer in postmenopausal women, according to a new study.
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