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Sunday, November 1, 2009

Maternal alcohol consumption may influence cord blood ascorbic acid concentration: findings from a study of Brazilian mothers and their newborns


Studies that have investigated ascorbic acid (AA) concentrations in cord blood have pointed to significant associations with maternal blood AA concentrations, smoking, age, diet, type of delivery, duration of gestation, fetal distress and birth weight.

The aim of the present study was to determine the relationship between cord blood AA concentrations in newborns and maternal characteristics.


The linear regression model including maternal AA concentration,
alcohol consumption, smoking, parity, vitamin C-rich food intake score and per capita income explained 31·13 % of the variation in cord blood AA concentrations in newborns.

We recommend further experimental studies to assess the effects of ethanol on placental AA uptake, and epidemiological cohort studies to evaluate in detail the influence of maternal
alcohol consumption on cord blood AA concentrations.

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