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Sunday, October 25, 2009

Linkage Analysis of Alcohol Dependence Symptoms in the Community
Alcoholism: Clinical and Experimental Research Early View 23 Oct 2009

We have previously identified suggestive linkage for alcohol consumption in a community-based sample of Australian adults. In this companion paper, we explore the strength of genetic linkage signals for alcohol dependence symptoms.

Suggestive peaks on chromosome 5p (LODs >2.2) were found in a region previously identified in alcohol linkage studies using clinical populations. Linkage signal strength was found to vary between full and truncated samples and when samples differed only on the collection age for a sample subset.

The results support the finding that large community samples can be informative in the study of alcohol-related traits.


Request Reprint E-Mail: Narelle.Hansell@qimr.edu.au

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