Aims

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Monday, March 19, 2007

Integrated Treatment to Persons With Mental Disorders and co-Occurring Substance Use Disorders (ROP)

This study is not yet open for patient recruitment.
Verified by SINTEF Health Research March 2007

Sponsors and Collaborators: SINTEF Health Research
The Research Council of Norway
University of Oslo
Information provided by: SINTEF Health Research
ClinicalTrials.gov Identifier: NCT00447733

Purpose

The purpose of this study is to determine whether integrated treatment is effective in the treatment of mental disorders and co-occurring substance use disorders.
Condition Intervention Phase
Anxiety Disorders
Mood Disorders
Substance Use Disorders
 Behavior: Integrated mental health and substance misuse treatment
 Phase II
Phase III

MedlinePlus related topics: Anxiety; Drug Abuse; Mental Health

Study Type: Interventional
Study Design: Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study

Official Title: Effects of Integrated Treatment to Persons With Mental Disorders and co-Occurring Substance Use Disorders

Further study details as provided by SINTEF Health Research:
Primary Outcomes: alcohol and drug use at baseline, six and twelve months; Psychopathology at baseline, six and twelve months; Global functioning at baseline, six and twelve months
Secondary Outcomes: Quality of life at baseline, six and twelve months; Therapist alliance at six and twelve months; Treatment fidelity at six and twelve months
Expected Total Enrollment: 150

Study start: March 2007; Expected completion: December 2008

Patients with mental disorders and co-occuring substance use disorders are characterized by high suicide and treatment drop-out rates, and long-lasting interpersonal, work, school, health and legal problems. And because mental disorders and substance use disorders interact and co-exists, it may be important to provide treatment that integrates their substance misuse and mental health problems in a comprehensive way. The health services for patients with mental health and substance use disordes are usually provided by different services and health professionals that rarely cooperate or have qualifications on both kinds of disorders. The over-all aim of the study is to evaluate the effects of evidence-based integrated and comprehensive treatment of mental health problems and co-occurring substance use disorders. The effects of the treatment will be assesses on substance use,psychopathology, and quality of life.

Comparison: patients receiving treatment-as-usual or non-manualized treatment at general mental health outpatients clinics.

Eligibility

Ages Eligible for Study: 18 Years and above, Genders Eligible for Study: Both
Criteria

Inclusion Criteria:

  • clinical diagnosis of substance use disorder
  • clinical diagnosis of anxiety disorders
  • clinical diagnosis of nonpsychotic mood disorders
  • written consent
  • planning to live in the catchment area during the treatment

Exclusion Criteria:

  • schizophrenia spectrum disorders
  • other psychotic disorders
  • mental retardation
  • having nicotine abuse/dependency only

Location and Contact Information

Please refer to this study by ClinicalTrials.gov identifier NCT00447733
Rolf W. Grawe, Ph.D 92221971 Ext. 0047 rolf.w.grawe@sintef.no
Amund Aakerholt, Ph.D 97599473 Ext. 0047 amund.aakerholt@iris.no

Norway
SINTEF Health Research, Trondheim, 7465, Norway
Rolf W. Gråwe, Ph.D 92221971 Ext. 0047 rolf.w.grawe@sintef.no

Study chairs or principal investigators

Rolf W. Gråwe, Ph.D, Principal Investigator, SINTEF Health Research

More Information

substance abuse treatment for persons with co-occurring disorders

Study ID Numbers: 78i068; NFR175394/V50
Last Updated: March 14, 2007
Record first received: March 14, 2007
ClinicalTrials.gov Identifier: NCT00447733
Health Authority: Norway: Norwegian Social Science Data Services
ClinicalTrials.gov processed this record on 2007-03-19
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