Psychological factors such as motivation to change and self-efficacy influence  drinking outcomes in alcohol-dependent individuals who are enrolled in  pharmacobehavioral studies. Previous results from our research clinic indicated  that initial stage of change of heavy drinkers enrolled in a pharmacobehavioral  trial was significantly associated with alcohol consumption. However, overall  empirical findings regarding the consistency and extent of the connection  between motivational factors and behavior are mixed. This may be in part because  of the impact of changes in motivation over the course of treatment and/or  characteristics of the individuals receiving the intervention. 
Our goal in the present study was to examine the extent to which levels of motivation and self-efficacy changed during the treatment phase of a pharmacobehavioral treatment trial, and the extent to which these variables affected drinking behavior in subsets of alcohol-dependent individuals.
Our goal in the present study was to examine the extent to which levels of motivation and self-efficacy changed during the treatment phase of a pharmacobehavioral treatment trial, and the extent to which these variables affected drinking behavior in subsets of alcohol-dependent individuals.
 We conducted an exploratory evaluation of changes in  motivation, temptation to drink, confidence to abstain, and drinking behavior  over time during the treatment phase of a pharmacobehavioral study involving 321  alcohol-dependent individuals. We also examined the extent to which individual  variables such as initial drinking severity, onset of alcohol dependence, and  medication status influenced changes in motivation, self-efficacy, and drinking  behavior.
 Participants reported improvements in motivation to change,  self-efficacy for change, and drinking behaviors over the course of treatment.  As hypothesized, motivation to change and self-efficacy for change were related  to specific dimensions of posttreatment drinking. Heavy drinkers reported more  improvement in drinking behaviors than did nonheavy drinkers. Early-onset  drinkers who were on medication reduced their drinking more than those on  placebo, and these drinking changes appear to be partially mediated by  reductions in temptation.
 Reductions in drinking occur and are predicted by  increased motivation to change, reduced temptation to drink, and increased  confidence to abstain in this population of alcoholic-dependent individuals.  Early and late onset and heavy drinkers and those taking medications displayed  differential changes in drinking behavior, some of which were explained by the  mediating effects of self-efficacy. This is a first step in understanding more  about which alcoholic individuals respond best to treatment and what mechanisms  may be involved in the changes in drinking and drinking-specific changes in  frequency and intensity of drinking.
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Request Reprint E-Mail: jkp2n@virginia.edu

 
