British Journal of Surgery Volume 96, Issue 11 (November 2009) p.1315-1322
Several epidemiological studies have been published, but there are few reports on relations between gallstone incidence, symptomatology and risk factors.
A positive association for gallstone development was found only for length of follow-up and plasma low-density lipoprotein-cholesterol levels at baseline. Weekly alcohol consumption was inversely related to gallstone development.The incidence of gallstones in this population was 1·39 per 100 person-years.
Gallstone development was related to length of follow-up and LDL-cholesterol levels, and inversely related to alcohol consumption.
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