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Thursday, June 25, 2009

Short-Term Alcohol Administration Alters KiSS-1 Gene Expression in the Reproductive Hypothalamus of Prepubertal Female Rats
Alcoholism: Clinical and Experimental Research Published Online: 10 Jun 2009

Alcohol causes suppressed KiSS-1 gene expression in the reproductive hypothalamus; hence, contributing to this drug's ability to cause suppressed LHRH secretion and disruption of the pubertal process. We suggest that this action, at least in part, is through altered IGF-1 signaling.

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Request Reprint E-Mail: ldees@cvm.tamu.edu
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