Aims

To support the free and open dissemination of research findings and information on alcoholism and alcohol-related problems. To encourage open access to peer-reviewed articles free for all to view.

For full versions of posted research articles readers are encouraged to email requests for "electronic reprints" (text file, PDF files, FAX copies) to the corresponding or lead author, who is highlighted in the posting.

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Thursday, June 25, 2009

A safety and tolerability laboratory study of the combination of aripiprazole and topiramate in volunteers who drink alcohol
Human Psychopharmacology: Clinical and Experimental Published Online: 23 Jun 2009

There was no evidence that adverse effects of aripiprazole and topiramate are additive and can, therefore, be administered safely together with a modest amount of alcohol. There was also a trend for a reduction of alcohol use by participants. This finding has implications for further investigation of this combination of drugs for alcohol dependence.


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