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Thursday, June 4, 2009

Adolescent ethanol experience alters immediate and long-term behavioral responses to ethanol odor in observer and demonstrator rats.
Behavioral and Brain Functions 2009, 5:23

In contrast to previous studies showing odor aversivion following acute ethanol intoxication, within the context of the social transmission paradigm, adolescent demonstrators like observers showed an enhanced behavioral response to ethanol odor. The differential enhanced odor response between observers and demonstrators, despite similar net enhancements relative to controls, suggests the presence of a stress effect from the infusion technique. This finding contrasts previous suggestions that intragastric infusions create minimal stress: an important consideration when conducting ethanol research. This stress effect appears to ameliorate by adulthood

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