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Monday, October 1, 2007

Body mass index, alcohol, tobacco and symptomatic gallstone disease: a Swedish twin study
Journal of Internal Medicine (OnlineEarly Articles). 1 October 2007



Both genetic and environmental factors are involved in the pathogenesis of gallstone disease (GD).

We aimed to examine the association between symptomatic GD and overweight (body mass index, BMI, 25–30 kg m-2), obesity (BMI > 30 kg m-2), alcohol, smoking and smoke-free tobacco by analysing a large twin population.

Consistent with epidemiological studies, we found positive associations between BMI and the development of symptomatic GD. High alcohol consumption was associated with a decreased risk against GD. Tobacco use has no impact on GD.

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Reprint Request E-Mail: despina.katsika@ki.se

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