• Heavy alcohol consumption accelerates telomere shortening.
• Telomere shortening is linked to premature aging and cancer risk.
WASHINGTON, D.C. — Researchers have detected a link between alcohol consumption, cancer and aging that starts at the cellular level with telomere shortening.
Results of this cross-sectional study were presented at the American Association for Cancer Research 101st Annual Meeting 2010, held here, April 17-21, at the Walter E. Washington Convention Center.
Telomeres are found at the region of DNA sequences at the end of a chromosome, and are important for the genetic stability of cells. As people age, telomere length shortens progressively.
Excessive use of alcohol has been linked to oxidative stress and inflammation, two mechanisms that accelerate telomere shortening. Since telomere shortening is thought to increase cancer risk, the researchers speculated that those with shorter telomeres due to heavy alcohol consumption would have an increased risk of cancer. . . . . . .
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