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Tuesday, June 30, 2009

Intermittent access to beer promotes binge-like drinking in adolescent but not adult Wistar rats
Alcohol Volume 43, Issue 4, June 2009, Pages 305-314

Teenagers are more likely than adults to engage in binge drinking and could be more vulnerable to long-term brain changes following alcohol abuse. We investigated the possibility of excessive adolescent drinking in a rodent model in which beer (4.44% ethanol vol/vol) is presented to adult and adolescent male Wistar rats.

Adolescent groups consumed more alcohol than adults and showed higher BACS that were typical of human “binge” drinking (>80 mg/dL). Despite this, the correlation between BAC and beer intake was similar in both age groups.

Together these results show that the intermittent presentation of alcohol itself appears to have subtle long-lasting effects on the motivation to consume alcohol. The findings support the use of beer solutions in modeling binge-like patterns of human alcohol consumption in adolescent rats.


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