Aims

To support the free and open dissemination of research findings and information on alcoholism and alcohol-related problems. To encourage open access to peer-reviewed articles free for all to view.

For full versions of posted research articles readers are encouraged to email requests for "electronic reprints" (text file, PDF files, FAX copies) to the corresponding or lead author, who is highlighted in the posting.

___________________________________________

Thursday, April 21, 2011

Targeting Alcohol-Induced Epigenetic Changes: A Pharmacotherapeutic Approach for Alcoholism Treatment



Alcoholism is a significant worldwide health problem, and yet current therapeutic approaches do not consistently prevent relapse. Epigenetics is an emerging science, providing fresh insight into developmental mechanisms preceding many diseases. Research over the last decade has exposed ethanol as an agent capable of producing epigenetic changes associated with alcohol tolerance, dependence, craving, and tissue toxicity. 

This article outlines research into these ethanol-mediated changes and possible directions for future pharmacotherapy treatments for alcohol-related disorders.



Request Reprint E-Mail: