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Thursday, May 7, 2009

Gene–environment interactions and alcohol use and dependence: current status and future challenges
Addiction Volume 104 Issue 6, Pages 907 - 914

Challenges for future gene–environment studies are abundant, and consist of, for example, the development of clear theoretical assumptions about neurobiological mechanisms and the recruitment of large longitudinal samples that already start in childhood. Replication is essential to prevent an overload of false-positive results. Despite the difficulties, it is crucial to include gene–environment interactions in future studies in order to unravel the aetiological factors of human alcohol outcomes.

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