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Friday, January 9, 2009

Central Neuropeptide Y in Anxiety- and Stress-related Behavior and in Ethanol Intake
Annals of the New York Academy of Sciences Volume 1148 Issue Stress, Neurotransmitters, and Hormones
Neuroendocrine and Genetic Mechanisms, Pages 136 - 140
One of the most profound properties of central neuropeptide Y (NPY) is its anxiolytic, or anti-anxiety, effect. This has been demonstrated repeatedly in a number of animal models. In addition, stressors affect NPY expression in the central nervous system, with acute and repeated (chronic) stress having differential effects.
Here, a brief summary of some work performed in our laboratory is presented that supports a role for NPY in regulation of stress responses and behaviors.
Request Reprint E-Mail: annika.thorsell@mail.nih.gov
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