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Thursday, July 3, 2008

Breast Cancer: Research Lends Biologic Plausibility to Link with Alcohol; Even Minimal Exercise May Lower
Oncology Times:Volume 30(12)25 June 2008p 55-56

Laino, Charlene

SAN DIEGO-The risk of hormone-receptor positive breast cancer is increased by as little as a drink or two a day, according to the largest study to look at the association between the two to date.

A second study shows that variations within two genes coding for the alcohol dehydrogenase enzyme (ADH) that is involved in metabolizing alcohol affect the risk of breast cancer in postmenopausal women.

The studies lend biologic plausibility to the fairly strong epidemiologic link between alcohol consumption and breast cancer, suggesting that drinking may affect risk through hormonal and genetic pathways, said Chi-Chen Hong, PhD, Assistant Professor of Oncology at the Roswell Park Cancer Institute.

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