New Haven, Conn. — Some change in the environment in many East Asian communities during the past few thousand years may have protected residents from becoming alcoholics, a new genetic analysis conducted by Yale School of Medicine researchers suggests.
The study by Hui Li and others in the laboratory of Kenneth Kidd, professor of genetics, psychiatry and ecology & evolutionary biology, will be released April 2, in the journal PloS One.
Scientists have long known that many Asians carry variants of genes that help regulate alcohol metabolism. Some of those genetic variants can make people feel uncomfortable, sometimes even ill, when drinking small amounts of alcohol. As a result of the prevalence of this gene, many, but not all, communities in countries such as China, Japan and Korea have low rates of alcoholism.
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