Associations of Alcohol Drinking and Cigarette Smoking with Serum Lipid Levels in Healthy Middle-Aged MenAlcohol and Alcoholism Advance Access published online on February 18, 2008
The aim of this study is to determine whether influences of drinking alcohol on serum lipid levels are different in smokers and non-smokers.
In overall subjects, serum HDL, LDL and total cholesterol were significantly lower and triglyceride was significantly higher in heavy smokers than in non-smokers. In the smoker groups, serum total cholesterol was significantly lower in heavy drinkers than in non-drinkers, while no difference in total cholesterol was observed in non- and heavy drinkers of the non-smoker group. Both in the smoker and non-smoker groups, HDL cholesterol was higher and LDL cholesterol was lower in drinkers than in non-drinkers. The difference in LDL cholesterol between non-drinkers and drinkers was more prominent in smokers than in non-smokers. The above associations were not altered after the adjustment for age, body weight and alcohol intake.
The results suggest that smoking increases the lowering effect of alcohol drinking on LDL cholesterol, but does not affect the relationship of alcohol drinking with HDL cholesterol.
Request E-Mail: wakabaya@hyo-med.ac.jp
________________________________________________________________
