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Friday, September 7, 2007

Alcohol consumption and endometrial cancer risk: The multiethnic cohort
International Journal of Cancer Early View Published Online: 31 Aug 2007



The role of alcohol intake in the etiology of endometrial cancer is unclear.

We examined the impact of alcohol intake on endometrial cancer risk among 41,574 postmenopausal African-American, Japanese-American, Latina, Native-Hawaiian and White women recruited to the prospective Multiethnic Cohort Study in 1993-1996.

Increased alcohol consumption was associated with increased risk Compared to nondrinkers, women consuming 2 drinks/day had a multivariate RR of 2.01 . There was no increase in risk associated with <1 drink/day and 1 to <2 drinks/day. There was no clear effect modification by body mass index, postmenopausal hormone use, parity, oral contraceptive use or smoking status, though our power to detect such interactions was limited.

Our results suggest that only alcohol consumption equivalent to 2 or more drinks per day increases risk of endometrial cancer in postmenopausal women.

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