Aims

To support the free and open dissemination of research findings and information on alcoholism and alcohol-related problems. To encourage open access to peer-reviewed articles free for all to view.

For full versions of posted research articles readers are encouraged to email requests for "electronic reprints" (text file, PDF files, FAX copies) to the corresponding or lead author, who is highlighted in the posting.

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Tuesday, July 29, 2008

Chronic intake of fermented floral nectar by wild treeshrews
PNAS Early Edition 28 July 2008


For humans alcohol consumption often has devastating consequences. Wild mammals may also be behaviorally and physiologically challenged by alcohol in their food. Here, we provide a detailed account of chronic alcohol intake by mammals as part of a coevolved relationship with a plant.

We discovered that seven mammalian species in a West Malaysian rainforest consume alcoholic nectar daily from flower buds of the bertam palm (Eugeissona tristis), which they pollinate. The 3.8% maximum alcohol concentration (mean: 0.6%; median: 0.5%) that we recorded is among the highest ever reported in a natural food. Nectar high in alcohol is facilitated by specialized flower buds that harbor a fermenting yeast community, including several species new to science.

Pentailed treeshrews (Ptilocercus lowii) frequently consume alcohol doses from the inflorescences that would intoxicate humans. Yet, the flower-visiting mammals showed no signs of intoxication. Analysis of an alcohol metabolite (ethyl glucuronide) in their hair yielded concentrations higher than those in humans with similarly high alcohol intake.

The pentailed treeshrew is considered a living model for extinct mammals representing the stock from which all extinct and living treeshrews and primates radiated. Therefore, we hypothesize that moderate to high alcohol intake was present early on in the evolution of these closely related lineages.

It is yet unclear to what extent treeshrews benefit from ingested alcohol per se and how they mitigate the risk of continuous high blood alcohol concentrations.

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Request Reprint E-Mail: frank.wiens@uni-bayreuth.de

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Monday, July 28, 2008

Media Release - New Study into Alcohol Abuse
Exposes ‘Beer-Binge’ as Real Problem


2 June 2008

Australians who consume alcohol at dangerous levels drink eight times more beer than any other alcoholic product, according to a major research report released today.

The study, produced by Roy Morgan Research and released to DSICA, exposes beer as the dominant drink of choice among Australians considered heavy drinkers (consuming more than 100 drinks per month). See attached key findings.

. . . . . .

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Personality Traits Predict Treatment Outcome in Alcohol-Dependent Patients
Neuropsychobiology 2008;57:159-164


Personality traits are important individual characteristics modifying responses to therapy in various diseases. The aim of this study was to identify personality traits that may predict treatment outcome in alcohol-dependent patients.

The present analysis was based on a total of 146 alcohol-dependent patients (109 male, 37 female) after detoxification. The variable of interest was treatment outcome (abstinence/relapse) after a 1-year follow-up. To identify personality traits as predictors of treatment outcome, 5 personality questionnaires (NEO 5-Factor Inventory, Temperament and Character Inventory, Eysenck Personality Questionnaire, Eysenck Impulsiveness-Venturesomeness-Empathy Scale and Sensation-Seeking Scale) were applied. Data analysis was performed by using a classification and regression tree analysis (CART; a nonparametric technique for data with a complex structure) in order to find a decision rule to predict treatment outcome from personality traits.

The CART model identified psychoticism and persistence as the 2 most relevant discriminatory parameters, of which psychoticism was used as the first node in the model, classifying 64% of the patients correctly as relapsed and 12% correctly as abstinent. In addition, the risk of relapse was even higher in patients with a substantial score in psychoticism and a low score in persistence. When comparing relapsed and abstinent patients, further variables, such as scores for novelty seeking (20.9 ± 5.5 vs. 18.5 ± 5.9) and impulsiveness (8.4 ± 3 vs. 7.2 ± 3.5), showed significance. In addition, relapsed patients lived alone more often than abstinent patients (52 vs. 25%, p = 0.004).

In conclusion, this analysis demonstrated that specific personality characteristics, namely psychoticism and persistence, are usable predictors for the risk of relapse in alcohol-dependent patients.

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Request Reprint E-Mail: sandra.mueller@upkbs.ch
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Opinion - Why would you listen to alcohol lobbyists on health issues?
  • Gino Vumbaca
  • July 29, 2008

Health experts are best qualified to advise the Government on alcohol.

THE liquor industry's reaction to the increase in the alcopop taxation has been loud, vitriolic and uncompromising. More than that, the debate on alcohol taxation has given an interesting insight into the power and influence of the liquor industry.

Every day seems to bring yet another press release questioning the increased tax rate on some alcopops. The latest is yesterday's announcement by the Liquor Merchants Association of Australia that while there was a 30% fall in the volume of ready-to-drink alcohol sold between April and June, sales of full-strength bottled spirits over the same period increased by 46%.

It's not just media releases. Spending some of their substantial corporate profits to campaign against the Government in the Gippsland byelection was considered fair by one part of the industry in the battle for public support.

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Alcopop tax increased drink sales: distillers

Jessica Irvine Economics Correspondent
July 28, 2008

DISTILLERS have stepped up their campaign against the Federal Government's controversial "alcopops" tax rise, releasing figures today showing the overall number of standard drinks sold each month - including alcopops and full-strength spirits - has increased by 10 per cent since the tax was raised three months ago.

The Distilled Spirits Industry Council of Australia said this was evidence the attempt to stop binge drinking had failed. It said the figures showed the decrease in sales of "ready to drink" beverages had been more than offset by an increase in full-strength spirits sales.

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Alcohol-attributable fractions for England

The most up-to-date review of the relationships between alcohol consumption and alcohol-related harms. This report examines the major causes of ill-health and mortality due to alcohol and determines what proportion of cases in England are caused by alcohol. Figures presented include the latest data for levels of hospital admission and number of deaths.

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Saturday, July 26, 2008

Introducing The Bridge and an Invitation for Contributions




The Bridge is a quarterly e-pub that links science and service by providing information and tools on technology transfer and implementation science strategies.

Volume 1, Issue 1
In this Issue...

> Introducing The Bridge
> Technology Transfer and American Culture
> From Bench to Bedside: A Useful Formulation?
> Exploring Key Concepts in Technology Transfer
> Technology Transfer in Manufacturing...
> A Heritage in the Field of Agriculture
> Introducing the Editor of The Bridge
> Introducing the Publisher of The Bridge


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International rapid evidence review of services for homeless people with substance misuse problems that considers models of service delivery and outcome measurement within a Scottish context.

A Rapid Evidence Assessment of international literature on effective substance misuse services for homeless people was conducted to review best practice in other countries and determine if there were any lessons for Scotland. The review found that:

* The relationship between substance misuse and homelessness appears quite complex. There is strong evidence of a mutually reinforcing relationship between these two social problems. An experience of homelessness increases the risk of substance misuse among previously abstinent people, while entering into substance misuse also increases the risk that someone will become homeless. There is evidence that when someone is homeless and involved in substance misuse each problem compounds the other ( Chapter 2).

* In Scotland, there is evidence that young homeless people, people with experience of sleeping rough and lone homeless people are characterised by higher rates of substance misuse than are found in the general population. There is evidence that parents and children in homeless families are either only a little more likely, or no more likely, to be involved in substance misuse than parents and children in the general population. The same pattern exists in England and in North America ( Chapter 2).

* There is a strong association between the presence of mental health problems or severe mental illness among homeless people with substance misuse problems in Scotland. The same pattern exists in England, the EU, North America and Japan ( Chapter 2).

* Services that are aimed solely at promoting abstinence among homeless people with a substance misuse problem tend to meet with quite limited success. There is evidence that many homeless people with a substance misuse problem either cease contact with these services before treatment or rehabilitation is complete or avoid such services to begin with. Attempts to use short stay detoxification services with homeless people have proven particularly unsuccessful ( Chapter 3).

* When services pursue harm reduction or harm minimisation policies, rather than insisting on total abstinence, there is evidence that they are able to engage with homeless people with a substance misuse problem more effectively. In particular, there is evidence that harm reduction based floating support models used in the United States are able to promote and sustain stable living arrangements and ensure contact with services ( Chapter 3).

* Homeless people with substance misuse problems have a range of needs that can include support with daily living skills, a requirement for mental health services and a requirement for support in managing substance misuse. Their needs are often complex and services that focus on any one element of their need, be it substance misuse, mental health or housing related support, meet with less success than services that are designed to support all their needs ( Chapters 2 and 3).

* There are three main models of resettlement for homeless people with a substance misuse problem. The first, the Continuum of Care or 'Staircase' approach, uses a series of shared supported housing settings that are intended to slowly progress service users towards independent living and abstinence. The evidence is that this model meets with limited success. The second, which is referred to in the US as the 'Pathways' Housing First model, uses intensive floating support to ordinary accommodation, with a strong focus on service user choice and a harm reduction approach to substance misuse. There is evidence that this is more successful and cost effective than the first model. The final model is a package of floating support provided through case management and joint working, which is the standard practice across Scotland. The evidence base on this approach is less developed than for some other models, though it follows the logic of both the flexible packages of support and harm reduction methods used by the more successful services ( Chapter 3).

* There is no strong evidence on the effectiveness of preventative services to counteract potential homelessness among people with a history of substance misuse. Most models of prevention are generic, i.e. they are intended to counteract the risk of homelessness across many groups, including people with a history of substance misuse, rather than being particularly focused on one group ( Chapter 3).

* The evidence base on alcohol misuse by homeless and potentially homeless people was very rich until the early 1980s when street drugs started to become much more widespread among street homeless and other homeless populations. Most research since that date has tended to focus on all forms of substance misuse, rather than dealing solely with alcohol, with the result that there is little recent evidence on services for homeless people that focus only on alcohol misuse. There is some evidence of older street homeless and hostel dwelling populations (people over 50) being more likely to be misusing alcohol and less likely to be using street drugs. However, among younger homeless people, the evidence is of use of alcohol alongside street drugs and other substances ( Chapter 2).

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Thursday, July 24, 2008

The Healthy Moms Study: The Efficacy of Brief Alcohol Intervention in Postpartum Women
Alcoholism: Clinical and Experimental Research Published Online: 9 Jul 2008

The prevention and treatment of alcohol use disorders among women of reproductive age have been well described. However, there is limited information on women specifically during the postpartum period. This period in a woman's life is a time of transition and it provides an ideal opportunity for primary care providers to intervene.

The goal of this report was to present the results of a brief alcohol intervention conducted in 34 obstetrical practices with women seeking routine postpartum care.

A total of 8,706 women were screened for high-risk alcohol use during routine postpartum care with 997 (12%) of these women testing positive for at-risk drinking. A total of 235 women met inclusion criteria and were randomized to either "usual care" or "brief intervention." The 4-session intervention was delivered by outpatient obstetrical nurses and research staff. The mean age of the women in the sample was 28, 19.3% were from minority groups, 60.8% were married, 53.2% reported current tobacco use, and 17.9% had used marijuana in the previous 30 days.

At the 6 month follow-up appointment, there were significant reductions in mean number of total drinks in the previous 28 days (p < class="i">p < class="i">p <>

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Request Reprint E-Mail: mfleming@fammed.wisc.edu

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Sound Level of Environmental Music and Drinking Behavior: A Field Experiment With Beer Drinkers
Alcoholism: Clinical and Experimental Research Published Online: 21 Jul 2008

It had been found that environmental music was associated with an increase in alcohol consumption. The presence versus absence of music, high versus slow tempo and the different styles of environmental music is associated with different level of alcohol consumption. However, the effect of the level of the environmental music played in a bar still remained in question.

The results show that high level volume led to increase alcohol consumption and reduced the average amount of time spent by the patrons to drink their glass.

The impact of environmental music on consumption was discussed and the "arousal" hypothesis and the negative effect of loud music on social interaction were used to explain our results.

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Request Reprint E-Mail: nicolas.gueguen@univ-ubs.fr

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Coffee and Cigarette Consumption and Perceived Effects in Recovering Alcoholics Participating in Alcoholics Anonymous in Nashville, Tennessee
Alcoholism: Clinical and Experimental ResearchPublished Online: 24 Jul 2008


Alcoholics Anonymous (AA) members represent an important and relatively understudied population for improving our understanding of alcohol dependence recovery as over 1 million Americans participate in the program. Further insight into coffee and cigarette use by these individuals is necessary given AA members' apparent widespread consumption and the recognized health consequences and psychopharmacological actions of these substances.

Mean (±SD) age of onset of alcohol consumption was 15.4 ± 4.2 years and mean lifetime alcohol consumption was 1026.0 ± 772.8 kg ethanol. Median declared alcohol abstinence was 2.1 years (range: 0 days to 41.1 years) and median lifetime AA attendance was 1000.0 meetings (range: 4 to 44,209 meetings); average AA affiliation score was 7.6 ± 1.5. Most (88.5%) individuals consumed coffee and approximately 33% of coffee consumers drank more than 4 cups per day (M = 3.9 ± 3.9).

The most common self-reported reasons for coffee consumption and coffee-associated behavioral changes were related to stimulatory effects. More than half (56.9%) of individuals in AA smoked cigarettes. Of those who smoked, 78.7% consumed at least half a pack of cigarettes per day (M = 21.8 ± 12.3). Smokers' FTND scores were 5.8 ± 2.4; over 60% of smokers were highly or very highly dependent. Reduced negative affect was the most important subjective effect of smoking.

A greater proportion of AA participants drink coffee and smoke cigarettes in larger per capita amounts than observed in general U.S. populations. The effects of these products as described by AA participants suggest significant stimulation and negative affect reduction.

Fundamental knowledge of the quantitative and qualitative aspects of coffee and cigarette consumption among AA members will enable future research to discern their impact on alcohol abstinence and recovery.

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Request Reprint E-Mail: peter.martin@vanderbilt.edu

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European ECAT conference: 'Empower the Community in response to Alcohol Threats'

VAD and the ECAT network have the pleasure of inviting you to the European ECAT conference: 'Empower the Community in response to Alcohol Threats'

Friday 24 October 2008
Flemish Parliament | Leuvenseweg 86 | 1000 Brussels | Belgium

ECAT is an EC-co-funded project that aims to enhance the effectiveness of local alcohol prevention campaigns, based on:

· guidelines for local campaigning, built on evidence based practice;

· local quick scan analysis to describe the local situation on alcohol use, as a starting point to develop local actions and more specifically local alcohol prevention campaigns;

· evaluation of the reach and visibility of the local alcohol prevention campaigns.

We present the conceptual frame of the ECAT methodology and the field experiences in the local communities of the participating countries: Great Britain, Germany, Austria, Slovenia, Italy and Belgium.
. . . . . .

Read Full Announcement (PDF)
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Epidemiology for Researchers Performing Genetic/Genomic Studies

This is a short course targeted at investigators and trainees doing research in human genetics, particularly studies employing genomic analyses of samples from human population. It aims to familiarize researchers studying the human genome with basic principles and potential pitfalls of epidemiology as applied to human genome research. It will draw from traditional genetic epidemiology and statistical genetics, but will emphasize the application of genomic technologies to unrelated subjects in human populations. Focus will be on the design, conduct, analysis, and interpretation of the epidemiologic studies most feasible and appropriate to address the genomic questions of interest.

Click Here to Play Video.  This video is world accessible.


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Expert view: Alcohol consumption

Many in the medical industry are worried that drinkers aren’t aware of increasing strengths of wine - not to mention bigger glasses

n the north-west of England one person is admitted to hospital with an alcohol-related illness every seven seconds so we are very clear that alcohol consumption is a significant concern. The interventions proposed today are welcome in helping to get a cultural shift in the way people consume alcohol. Part of that is to provide information but obviously it’s more than that and today’s proposals cover a whole range of things that will help people consider their personal alcohol consumption.
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Drinks industry regulation: 'The government are nervous about taking a tough stance'

Health editor Sarah Boseley on plans to better regulate the alcoholic drinks industr
  • Wednesday July 23 2008


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Wednesday, July 23, 2008

Psychometric properties of the alcohol use disorders identification test: a Korean version.
Archives of Psychiatric Nursing Volume 22, Issue 4, August 2008, Pages 190-199

The Alcohol Use Disorders Identification Test (AUDIT) is an important screening tool but has never been administered to Korean Americans. This study was conducted to examine the psychometric properties of a Korean version of the AUDIT referred to as AUDIT-K and to determine which cutoff score of the scale would perform better in Korean Americans.

Approximately 47.5% of Korean American men who participated in the study were identified as having drinking problems when using the World Health Organization's recommended cutoff score of 8, whereas approximately 20.3% were found to have problems with alcohol when using the cutoff score of 12, the one recommended for Koreans. Cronbach's alpha was .82 at Time 1 and was .80 at Time 2. Test–Retest reliability assessed via the intraclass correlation coefficient for the total AUDIT scale was .85. Principal components factor analysis with varimax orthogonal rotation revealed a two-factor solution, alcohol consumption and drinking problems, resulting in 57% of the explained variance.

The AUDIT-K was found to be internally consistent and stable over time and should be used in primary health care settings to screen Korean American men for alcohol use disorders to facilitate early interventions.

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Request Reprint E-Mail: sun.kim@umassmed.edu

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Family Meals and Substance Use: Is There a Long-Term Protective Association?
Journal of Adolescent Health Volume 43, Issue 2, August 2008, Pages 151-156
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To examine 5-year longitudinal associations between family meal patterns and subsequent substance use in adolescents.

Family meal frequency at baseline was associated with significantly lower odds of cigarette smoking, alcohol use, and marijuana use at follow-up among female adolescents, even after adjusting for baseline substance use and additional covariates. Family meals were not associated with use of any substance at follow-up for male adolescents after adjusting for baseline use.

Results from this study suggest that regular family meals in adolescence may have a long-term protective association with the development of substance use over 5 years among females. Parents should be encouraged to establish a pattern of regular family meals, as this activity may have long lasting benefits

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Request Reprint E-Mail: eisen012@umn.edu

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New Strategies to Detect Alcohol Use Disorders in the Preoperative Assessment Clinic of a German University Hospital.
Anesthesiology. 109(2):171-179, August 2008.

Although alcohol use disorders (AUDs) have enormous public health consequences, the rate of diagnosis of AUDs remains unsatisfactorily low. The primary aim of this study was to compare the detection of AUDs by anesthesiologists in a large preoperative assessment clinic to that by computerized self-assessment of the Alcohol Use Disorder Identification Test. Secondary outcome measures were to compare the actions taken by anesthesiologists upon a finding of an AUD.

The prevalence rate of AUDs determined by the anesthesiologists was 6.9% (107 of 1,556), whereas the proportion of patients positive for an AUD using the computerised Alcohol Use Disorder Identification Test was 18.1% (282 of 1,556) (P <>

The computer-based self-assessment increases detection rates of AUDs in busy settings such as a preoperative assessment clinic. Prevalence rates of AUDs are underestimated. Best-practice guidelines for detection of AUDs are not implemented in the daily clinical routine. Barrier analysis is urgently required.

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'A culture of intoxication'

High-risking drinking still a big problem in N.S.


Nova Scotia still has a drinking problem.

People in the province still drive drunk, still go on benders at bars, still drink underage and some drink while pregnant.

To combat this, last August the provincial Department of Health Promotion and Protection launched a strategy called Changing the Culture of Alcohol Use in Nova Scotia.

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News Release - CALIFORNIA ALCOHOL PROBLEMS DRAIN $38 BILLION ANNUALLY

Los Angeles, CA (July 23, 2008) --- Marin Institute, the alcohol industry watchdog, held a news conference and town hall meeting in Los Angeles today to release the disturbing findings of its landmark report, The Annual Catastrophe of Alcohol in California. Such a comprehensive study has never been done in California.

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