Associations Among GABRG1, Level of Response to Alcohol, and Drinking Behaviors

Alcoholism: Clinical and Experimental Research Published Online: 4 May 2009

Analyses revealed that a SNP of the GABRG1 gene (rs1497571) was associated with level of response to alcohol and drinking patterns in this subclinical sample. Follow-up mediational analyses were also conducted to examine putative mechanisms underlying these associations.

These findings replicate and extend recent research suggesting that genetic variation at the GABRG1 locus may underlie the expression of alcohol phenotypes, including level of response to alcohol.

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