Update on the Genetics of Alcoholism

261 Letter From the Acting Director [PDF]

263 Editors’ Note [PDF]

264 In This Issue [PDF]

266 Overview: Assessing the Genetic Risk for Alcohol Use Disorders [PDF]
Tatiana Foroud, Ph.D., and Tamara J. Phillips, Ph.D.

270 Genetics Primer [PDF]

274 Identifying Genetic Variation for Alcohol Dependence [PDF]
Arpana Agrawal, Ph.D., and Laura J. Bierut, M.D.

282 Using Genetically Engineered Animal Models in the Postgenomic Era to Understand Gene Function in Alcoholism [PDF]
Matthew T. Reilly, Ph.D.; R. Adron Harris, Ph.D.; and Antonio Noronha, Ph.D.

293 Epigenetics—Beyond the Genome in Alcoholism [PDF]
Bela G. Starkman; Amul J. Sakharkar, Ph.D.; and Subhash C. Pandey, Ph.D.

306 Identifying Gene Networks Underlying the Neurobiology of Ethanol and Alcoholism [PDF]
Aaron R. Wolen, Ph.D., and Michael F. Miles, M.D., Ph.D.

318 The Impact of Gene–Environment Interaction on Alcohol Use Disorders [PDF]
Danielle M. Dick, Ph.D., and Kenneth S. Kendler, M.D.

325 Bridging Animal and Human Models: Translating From (and to) Animal Genetics[PDF]
Amanda M. Barkley-Levenson and John C. Crabbe, Ph.D.

336 Genes Contributing to the Development of Alcoholism: An Overview[PDF]
Howard J. Edenberg, Ph.D.

339 Genes Encoding Enzymes Involved in Ethanol Metabolism[PDF]
Thomas D. Hurley, Ph.D., and Howard J. Edenberg, Ph.D.

345 Alcohol Dependence and Genes Encoding α2 and γ1 GABAA Receptor Subunits: Insights from Humans and Mice [PDF]
Cecilia M. Borghese, Ph.D., and R. Adron Harris, Ph.D.

355 Immune Function Genes, Genetics, and the Neurobiology of Addiction[PDF]
Fulton T. Crews, Ph.D.

362 Circadian Genes, the Stress Axis, and Alcoholism [PDF]
Dipak K. Sarkar, Ph.D., D.Phil.

367 Discovering Genes Involved in Alcohol Dependence and Other Alcohol Responses: Role of Animal Models [PDF]
Kari J. Buck, Ph.D.; Lauren C. Milner, Ph.D.; Deaunne L. Denmark, M.D., Ph.D.; Seth G.N. Grant, Ph.D.; and Laura B. Kozell, Ph.D.

375 Glossary [PDF]

378 Resources [PDF

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