- Genome-wide study of alcohol dependence points to chromosome 11
- Both genetic and environmental factors affect susceptibility to alcohol dependence (AD).
- To date, researchers have identified several genes associated with AD.
- Findings from a new genome-wide association study support an association between AD and a cluster of genes on chromosome 11.
Alcohol dependence (AD) is a complex disease for which both genetic and environmental factors affect susceptibility. Previous research had identified several genes associated with AD through linkage analysis or candidate-gene approaches. Findings from a genome-wide association study (GWAS) support an association between AD and a cluster of genes on chromosome 11.
Results will be published in the May 2010 issue of Alcoholism: Clinical & Experimental Research and are currently available at Early View. . . . . .
____________________________________________________