Alcohol Acutely Increases Vascular Reactivity together with Insulin Sensitivity in Type 2 Diabetic Men

Experimental and Clinical Endocrinology & Diabetes Online First 15 October 2009

Moderate alcohol consumption is associated with increased insulin sensitivity and reduced cardiovascular risk.

We hypothesized that this relates to a direct effect of alcohol and therefore investigated whether acute alcohol intake altered insulin sensitivity or endothelial function in patients with type 2 diabetes. .

We conclude that alcohol intake acutely increases endothelium-dependent brachial artery vasodilation in patients with type 2 diabetes together with insulin sensitivity.

This acute effect might explain some beneficial effects of low alcohol consumption in epidemiological observations.

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