Twin Pair Resemblance for Psychiatric Hospitalization in the Swedish Twin Registry: A 32-year Follow-up Study of 29,602 Twin PairsBehavior Genetics Volume 37, Number 4 / July, 2007
Allgulander et al. published twin pair analyses of psychiatric hospitalization for like-sex pairs from the Swedish Twin Registry born 1926–1958.
The present report updates the prior results by using 17 additional years of follow-up, including members of opposite-sex twin pairs, and addressing biases arising from cohort effects and from excluding pairs with unknown zygosity.
The present report updates the prior results by using 17 additional years of follow-up, including members of opposite-sex twin pairs, and addressing biases arising from cohort effects and from excluding pairs with unknown zygosity.
Inclusion of additional follow-up information, opposite-sex twin pairs, age-adjustment, and use of current ICD definitions yielded higher heritability estimates for alcoholism, anxiety disorders, and psychosis than previously published for this nationally-representative sample of twins from Sweden.
The results show that relatively small selection biases can alter twin study results and underscore the importance of addressing under-ascertainment of cases in genetic research based on volunteers.
Read Full Abstract
Reprint request E-Mail: cprescot@usc.edu
__________________________________________________________
The results show that relatively small selection biases can alter twin study results and underscore the importance of addressing under-ascertainment of cases in genetic research based on volunteers.
Read Full Abstract
Reprint request E-Mail: cprescot@usc.edu
__________________________________________________________