Tuesday, March 13, 2007

Are there empirically supported and clinically useful subtypes of alcohol dependence?

Addiction. 2006 Sep;101 Suppl 1:97-103





Department of Psychiatry, University of Connecticut School of Medicine, Farmington, CT, USA.

AIMS:

This paper provides an overview of several multidimensional empirically derived typologies of alcohol use disorders that have been derived primarily for research purposes in relation to their clinical utility.

METHODS:

Studies using multivariate statistical methods for identifying homogeneous groups of subjects were selected for inclusion. Theoretically based typologies were not included in this review.

RESULTS:

While formal diagnostic criteria typically identify separate categories of alcohol abuse and dependence, several studies using different statistical methods consistently suggest as many as four homogeneous types of alcoholism: a chronic/severe type, a depressed/anxious type, a mildly affected type and an antisocial type.

CONCLUSIONS:

Even though the longitudinal outcomes of few empirically derived subtypes have been examined, alcoholism typologies remain a viable and potentially valuable tool for investigating etiological pathways, the effectiveness of treatments and the long-term course of alcohol use disorders.